Novartis Open Source Initiative

Applied modelling in drug development: flexible Bayesian regression modelling in Stan via brms

A Python library for benchmarking uncertainty estimation and quantification methods for Machine Learning models predictions.

QM-ATLAS is a python package that orchestrates QM calculations. Based on thin wrappers of external software, more complex modules are built, exposing single calculation steps as well as multi-step workflows. The repository provides a flexible command-line interface that allows to define complex workflows in single configuration files.

Exploratory Graphics for PKPD data

A bslib toolkit for building modern, themeable dashboards in Shiny.

PISCES is a pipeline for rapid transcript quantitation, genetic fingerprinting, and quality control assessment of RNAseq libraries using Salmon.

Tool-set to support Bayesian evidence synthesis in R

Rscripts used to analyze single cell RNAseq data for "A Potent Macrocyclic pan-KRAS Inhibitor Drives Broad Antitumor Activity and Immune Remodeling" manuscript.

tinydenseR is a landmark-based platform for single cell data analysis that identifies differential cell states and features. Modeling samples as replicates, tinydenseR enhances analytic efficiency and reproducibility while preserving the richness of single cell data.